opioidfentanylharm-reductionA New Sedative Is Showing Up in New York's Drug Supply — and Naloxone Won't Stop ItDrug checking programs at NYC syringe service programs are detecting a new sedative in the city's opioid supply. Medetomidine is more dangerous than xylazine, and naloxone has no effect on it — which changes how overdoses need to be managed.February 18, 20263 min read